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Recreational inhalation of nitrous oxide, with the purpose of causing euphoria and/or slight hallucinations, began as a phenomenon for the British upper class in 1799, known as "laughing gas parties". The pharmacological mechanism of action of N2O in medicine is not fully known. , Nitrous oxide is a minor component of Earth's atmosphere, currently with a concentration of about 0.330 ppm.  Exactly how N2O causes the release of endogenous opioid peptides remains uncertain. It causes central nervous system (CNS) depression and euphoria with little effect on the respiratory system.  Today, the gas is administered in hospitals by means of an automated relative analgesia machine, with an anaesthetic vaporiser and a medical ventilator, that delivers a precisely dosed and breath-actuated flow of nitrous oxide mixed with oxygen in a 2:1 ratio. While relatively non-toxic, nitrous oxide has a number of recognised ill effects on human health, whether through breathing it in or by contact of the liquid with skin or eyes. , In August 2015, the Council of the London Borough of Lambeth (UK) banned the use of the drug for recreational purposes, making offenders liable to an on-the-spot fine of up to £1,000.. Nitrous oxide also may be used in a monopropellant rocket. , The machine to produce "Factitious Airs" had three parts: a furnace to burn the needed material, a vessel with water where the produced gas passed through in a spiral pipe (for impurities to be "washed off"), and finally the gas cylinder with a gasometer where the gas produced, "air", could be tapped into portable air bags (made of airtight oily silk). The reason for this was most likely that Wells, in January 1845 at his first public demonstration to the medical faculty in Boston, had been partly unsuccessful, leaving his colleagues doubtful regarding its efficacy and safety. The National Institute for Occupational Safety and Health recommends that workers' exposure to nitrous oxide should be controlled during the administration of anaesthetic gas in medical, dental and veterinary operators. The use of nitrous oxide in anaesthesia, however, can increase the risk of postoperative nausea and vomiting. Came from nitrogen fertilization coefficient of 0.46 neurotoxicity after extended exposure Because of the mentally/physically disabled or medically compromised.... Deflagrate at approximately 600 °C ( 1,112 °F ) at a pressure of 309 psi ( 21 atmospheres.. N2O is inert at room temperature and has few reactions [ 30 ] discrepancies... 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